Isaac Scientific Publishing

Modern Organic Chemistry Research

A Green and Solvent Free Protocol for the Synthesis of Bioactive Tetrahydrobenzo[C]Xanthene-8-Ones Using Novel Ionic Liquid L-Pyrrolidine-2-Carboxylic Acid Sulfate (LPCAS)

Download PDF (240.6 KB) PP. 1 - 4 Pub. Date: February 14, 2017

DOI: 10.22606/mocr.2017.21001


  • Vaibhav W. Godse
    Department of Chemistry, Deogiri College, Aurangabad, 431005, Maharashtra, India
  • Sunil N. Darandale

    Department of Chemistry, NACS College, Ahmednagar, 414001, Maharashtra, India
  • Bhaskar H. Zaware

    Department of Chemistry, NACS College, Ahmednagar, 414001, Maharashtra, India
  • Sahebrao S. Rindhe

    Department of Chemistry, R K M Mahavidyalaya, Ahmednagar, 414001, Maharashtra, India
  • Laszlo Kotai

    Chemical Research Center, Hungarian Academy of Sciences, P. O. Box 17, HU-1525, Budapest, Hungary
  • Rajendra P. Pawar*

    Department of Chemistry, Deogiri College, Aurangabad, 431005, Maharashtra, India


A simple, solvent free, highly efficient and eco-friendly protocol for the synthesis of tetrahydrobenzo[c] xanthene-8-ones derivatives using novel ionic liquid; L-pyrrolidine-2-carboxylic acid sulfate (LPCAS) as a catalyst has been reported. Important features of this methodology are excellent yield of products, cleaner reaction profile, environmentally friendly and the inexpensive catalyst.


Tetrahydrobenzo[c]xanthene-8-ones, ionic liquid, solvent free etc.


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